![]() The epidemiological situation displayed a slight improvement at the end of the first wave (week 1, 2021). Since then, over 695,489 cases and more than 13,000 deaths were confirmed by the end of February 2021. In Iraq, the first SARS-CoV-2 case was diagnosed in Febru. SARS-CoV-2 is highly infectious and has caused over 234 million confirmed cases of COVID-19 globally, including over 4.8 million deaths reported by the WHO as of October 3, 2021. On March 11, 2020, the WHO declared the COVID-19 outbreak a pandemic, affecting humans worldwide. A relative unknown coronavirus named “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)” was then identified as the causative agent of COVID-19. In late December 2019, an outbreak of pneumonia of unknown etiology was announced in Wuhan, China. This work provides molecular epidemiological insights into the spread variants of SARS-CoV-2 in Iraq, which are most likely imported from Europe. ![]() In silico analysis of NS7a with Q62stop found that this stop codon had no considerable effect on the function of NS7a. A notable frequency (43.33%) of stop codon mutation (NS7a Q62stop) was detected among the B.1.1.7 lineage sequences. Interestingly, the phylogenetic analysis showed that multiple strains of the B.1.1.7 lineage clustered closely with those from European countries. The B.1.1.7 lineage was predominant (80.20%) from February to May 2021, while only one B.1.351 strain was detected. We detected nine different lineages of SARS-CoV-2. Also, we performed an in silico study to predict the effect of the truncation of NS7a protein (ORF7a) on its function. To understand the molecular epidemiology of SARS-CoV-2 during the second wave in Iraq (2021), we sequenced 76 complete SARS-CoV-2 genomes using NGS technology and identified genomic mutations and proportions of circulating variants among these. As anticipated, the rapid increase in COVID-19 infections in Iraq in February 2021 is due to the introduction of variants of concern during the second wave of the COVID-19 pandemic. Genomic surveillance of SARS-CoV-2 has had a critical role in tracking the emergence, introduction, and spread of new variants, which may affect transmissibility, pathogenicity, and escape from infection or vaccine-induced immunity. An English language version has been soft-launched around Asia, while Japanese and Chinese editions are due later in the year.Since the first reported case of coronavirus disease 2019 (COVID-19) in China, SARS-CoV-2 has been spreading worldwide. Lineage 2: Revolution also has the scope to become even bigger as it gears up for a worldwide release. Netmarble's Lineage 2: Revolution has earned NCSoft $35 million in royalties so far. While NCSoft is enjoying success from its own release, it will also be benefiting from another huge South Korean game. However, this is based on a survey conducted by analytics firm WiseApp and may not be entirely accurate. It also comes with a companion chat app, MTalk, which hit second place on the local download charts.Įxact figures of Lineage M's overall performance have yet to be released, but The Korea Times reports that it has reached 9.7 million downloads already. The developer's claim that this the largest pre-registration campaign of a mobile game ever.ġ30 servers were set up to run the game, the largest number to have ever been run for a mobile game in the country. NCSoft's Lineage M has topped the iOS download and grossing charts within seven hours of its initial launch in South Korea.Īccording to NCSoft, Lineage M had already seen 5.5 million players pre-download the game ahead of its launch.
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